LIN Bin, ZHOU Zhipeng, JIANG Yu,HUANG Tingduan, ZENG Yangdong

( Department of Radiology , Affiliated Hospital of Guilin Medical University, Guilin 541001, China)

AbstractObjective To investigate the diagnostic performance of Gd-EOB-DTPA enhanced MRl for smallhepatocellular carcinoma ( sHCC) non-washout in portal venous phase with high risk for hepatocellular carcinoma( HCC ). Methods 44 patients with high-risk for HCC underwent Gd-E0B-D'TPA-enhanced MRl, in total 50nodules non-washout in portal venous phase and further pathological diagnosis was underwent by surgical reseetion orpuncture biopsy. The difference between groups of liver nodule image features and the diagnostic performance of the model based on the image features was analyzed, Results Among the nodule non-washout in the portal venous phaseof Gd-EOB-D'TPA enhaneed MRl, there were statistically significant differenees between sHCC and Non-sHCCgroups in nonrim-like enhaneement in arterial phase, transitional phase hypointensity, nodular capsule, restricteddiffusion in DWl, mild-moderate 'T2 hyperintensity, and hypointensity in T1WI( P<0. 05 ). Multivariate logisticregression analysis showed that the transitional phase hypointensity, nodular capsule were independent risk faetors forsHCC. The sensitivity, specificity and accuracy of transitional phase hypointensity, nodular capsule and thecombined diagnosis of sHCC non-washout in portal venous phase were 72.7%, 70.6%,72.0% , 78.8%, 94.1 %.84.0% and 93.9%, 70.6%, 86.0%, respectively. The areas under ROc curve were 0.717, 0.865 and 0.905.respeetively. Conclusion With high risk for HCC, Gd-E0B-DTPA enhaneed MRl has high diagnostic efficieney inportal venous phase non-washout hepatocellular. 'The combination of low signal during migration and analysis ofnodular capsule sign can further improve the diagnostic elficacy of Gd-E0B-'TPA which enhaneed the diagnosticefficiency of MRl in portal venous phase non-washout hepatocellular.Keywords: small hepatocellular carcinoma: Gd-EOB-TPA: washout in portal venous phase: transitional phase hypointensity

DOI:10.19296/j.cnki.1008-2409.2024-02-021

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